Carl Friedrich Otto Westphal (March 23, 1833 – January 27, 1890) was a German neurologist and psychiatrist from Berlin. He was the son of Otto Carl Friedrich Westphal (1800-1879) and Karoline Friederike Heine and the father of Alexander Carl Otto Westphal. He was married to Klara, daughter of the banker Alexander Mendelssohn.
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After receiving his doctorate, he worked at the Berlin Charité, and subsequently became an assistant at the department for the mentally ill under Wilhelm Griesinger (1817-1868) and Karl Wilhelm Ideler (1795-1860). In 1869 he became an associate professor of psychiatry, as well as a clinical instructor in the department for mental and nervous diseases, In 1874 he attained the title of full professor of psychiatry.
Westphal's contributions to medical science are many; in 1871 he coined the term "agoraphobia", when he observed that three male patients of his displayed extreme anxiety and feelings of dread when they had to enter certain public areas of the city.[1] He is credited with providing an early diagnosis of "pseudosclerosis", which is known today as hepatolenticular degeneration, and also demonstrated a relationship between tabes dorsalis (nerve degeneration in the spinal cord) and paralysis in the mentally insane.
Westphal is credited with describing a deep tendon reflex anomaly in tabes dorsalis that later became known as the "Erb-Westphal symptom" (named with neurologist Wilhelm Heinrich Erb- 1840-1921). His name is also shared with neurologist Ludwig Edinger (1855-1918) regarding the Edinger-Westphal nucleus, which is an accessory nucleus of the third oculomotor nerve (cranial nerve number III). He was the first physician to provide a clinical description of narcolepsy and cataplexy (1877). In 1880 French physician Jean-Baptiste-Édouard Gélineau (1828-1906) also described the two maladies, coining the term narcolepsie.[2]
A large portion of his written work dealt with diseases of the spinal cord and neuropathology. He trained a number of prominent neurologists and neuropathologists, including Arnold Pick, Hermann Oppenheim, Carl Moeli and Karl Wernicke. His son, Alexander Carl Otto Westphal (1863-1941) was also a psychiatrist, and is associated with the Westphal-Piltz syndrome (neurotonic pupillary reaction). Westphal, in addition to his multiple contributions to neurology and neuroanatomy, has been credited with introducing rational and non-censorious treatment to psychiatric hospitalization in Germany.
Michel Foucault credits Westphal for the birth of the modern homosexual, with his paper published in 1870 on 'contrary sexual feeling', in which he describes two people dealing with what would later come to be known as homosexuality. This appears to be one of the first medical accounts of sexuality as a psychiatric disorder.[3]